2021.09?至今????????中國科學(xué)院廣州生物醫(yī)藥與健康研究院，研究員，博士生導(dǎo)師
2013.03 ~ 2021.07??? 德國馬克思普朗克分子生物醫(yī)學(xué)研究所及明斯特大學(xué)醫(yī)學(xué)院，博士后
2007.09 ~ 2013.02 ???中國科學(xué)院上海生命科學(xué)研究院神經(jīng)科學(xué)研究所，博士（碩博連讀）
2003.09 ~ 2007.07 ???華東理工大學(xué)，學(xué)士
1、血管在器官發(fā)育和再生修復(fù)中的功能
2、造血干細(xì)胞與骨髓微環(huán)境的相互作用
1、 國家自然科學(xué)基金面上項(xiàng)目（2023-2026）：主持
2、 國家自然科學(xué)基金面上項(xiàng)目（2025-2028）：主持
3、廣東省人才引進(jìn)個人項(xiàng)目（2024-2027）：主持
4、廣州市基礎(chǔ)與應(yīng)用基礎(chǔ)研究（2024-2026）：主持
5、廣州市開發(fā)區(qū)創(chuàng)新類精英人才（2022-2027）：主持
6、國家重點(diǎn)研發(fā)計劃（2024-2027）：參與（項(xiàng)目骨干）
7、廣東省團(tuán)隊(duì)項(xiàng)目（2024-2029）：參與（課題負(fù)責(zé)人）
1、2019年 馬普分子生物醫(yī)學(xué)所突出工作獎
2、2019年 德國干細(xì)胞協(xié)會年會墻報獎
3、2016年 Gordon Research Conference旅行獎
4、2011年 第七屆歐洲斑馬魚會議墻報獎
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國際學(xué)術(shù)大會口頭報告
1、2018年 Gordon Research Conference, Endothelial cell phenotypes in health and disease
2、2018年 EMBL Conference, Hematopoietic stem cells from the embryo to the aging organism
3、2015年 Dutch German joint meeting of the Molecular Cardiology
4、2012年 Kloster Seeon Angiogenesis meeting
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代表性論文：
(1) Lihui Lin, Jing Zhong, Fuqing Jiang, Yu-Xiang Wang, Lan-Yue Ma, Jia-Xin Yang, Yu-Yan Li , Rong-Rong Gao, Huijian Feng, Baomei Cai, Ziyu Feng, Xin Zhou, Ya-Hai Shu, Pan Chen, Xue W , Chen-Leng Cai, Qiang Wang, Guangming Wu, Duanqing Pei, Shangtao Cao, Yang Liu, Guangdun Peng, Jiekai Chen,?Qi Chen. A single-cell time-series atlas of endothelial cell embryonic development.?Cell.?2026 Feb 16:S0092-8674(26)00049-8. doi: 10.1016/j.cell.2026.01.002.
(2)?Qi Chen#, Yang Liu#, Hyun-Woo Jeong, Martin Stehling, Van Vuong Dinh, Bin Zhou, Ralf H. Adams*. Apelin+ endothelial niche cells control hematopoiesis and mediate vascular regeneration after myeloablative injury.?Cell Stem Cell, 2019 Dec 5;25(6):768-783.e6. doi: 10.1016/j.stem.2019.10.006.?#Equal contribution
Cell Stem Cell專門評論文章: Mutualism in the Marrow 2019 Dec 5;25(6):731-733. doi: 10.1016/j.stem.2019.11.007.??
其它論文：
(1) ?Lan-Yue Ma, Zhao-Hua Deng, Ke Bai, Yan-Mei Yu, Yin Huang, Rong-Rong Gao, Yu-Yan Li, Xiao-Ling Li, Jia-Xin Yang, Ya-Hai Shu, Jinjin Ma, Yang Liu,?Qi Chen. A single-cell hematopoietic microenvironmental atlas reveals progressive maturation of bone marrow vascular niche.?Cell Regen. 2025 Dec 4;14(1):50. doi: 10.1186/s13619-025-00265-7.
(2) Yu-Xiang Wang, Zhao-Hua Deng, Yu-Yan Li, Ke Bai, Jinjin Ma*, Yang Liu*,?Qi Chen*. Function of hematopoiesis and bone marrow niche in inflammation and non-hematopoietic diseases.?Life Medicine. ?2025 Mar 26;4(3):lnaf015.
(3) Jing Zhong, Rong-Rong Gao, Xin Zhang, Jia-Xin Yang, Yang Liu*, Jinjin Ma*,?Qi Chen*. Dissecting endothelial cell heterogeneity with new tools.?Cell Regeneration. 2025 Mar 23;14(1):10.
(4) Jian-Wei Chen, Yu-Xiang Wang, Rong-Rong Gao, Lan-Yue Ma, Jing Zhong, Jia-Xin Yang, Zhao-Hua Deng, Yu-Yan Li, Xiao-Ling Li, Ya-Hai Shu, Wen-Jing Guo, Zi-Yuan Zhou, Xiao Yu Tian, Jinjin Ma, Yang Liu*,?Qi Chen*. CDK14 regulates the development and repair of lung.?Cell Death Discov. 2025 Jan 18;11(1):12.
(5) Rong-Rong Gao, Lan-Yue Ma, Jian-Wei Chen, Yu-Xiang Wang, Yu-Yan Li, Zi-Yuan Zhou, Zhao-Hua Deng, Jing Zhong, Ya-Hai Shu, Yang Liu*,?Qi Chen*. ATN-161 alleviates caerulein-induced pancreatitis.?J Genet Genomics. 2024 Dec;51(12):1447-1458.
(6) Zhao-Hua Deng, Lan-Yue Ma,?Qi Chen*, Yang Liu*. Dynamic crosstalk between hematopoietic stem cells and their niche from emergence to aging.?Bioessays. 2023 Jan 27;e2200121. doi: 10.1002/bies.202200121
(7) Zhao-Hua Deng, Jing Zhong, Hai-Lin Jiang, Hyun-Woo Jeong, Jian-Wei Chen, Ya-Hai Shu, Ming Tan, Ralf H Adams, Ke-Ping Xie,?Qi Chen*, Yang Liu*. Antipsychotic drugs induce vascular defects in hematopoietic organs.?FASEB J. 2022 Oct;36(10):e22538. doi: 10.1096/fj.202200862R
(8) Yang Liu#,?Qi Chen#, Hyun-Woo Jeong, Dong Han, J?rg Fabian, Hannes Drexler, Martin Stehling, Hans R. Sch?ler, Ralf H. Adams*. Dopamine signaling regulates hematopoietic stem and progenitor cell function.?Blood,?2021 Nov 25;138(21):2051-2065. doi: 10.1182/blood.2020010419.
Blood專門評論文章: Dopamine motivates stem cells for reward. Blood. 2021 Nov 25;138(21):2012-2014. doi: 10.1182/blood.2021013538. SCI引用8次
(9) Yang Liu#,?Qi Chen#, Hyun-Woo Jeong#, Bong-Ihn Koh, Emma Watson, Cong Xu, Martin Stehling, Bin Zhou, Ralf H. Adams*. A specialized bone marrow microenvironment for fetal haematopoiesis.?Nature Communications, 2022, 13 (1327). https://doi.org/10.1038/s41467-022-28775-x ?
(10) Qi Chen, Hui Zhang, Yang Liu, Dagmar Zeuschner, Monica Corada, Elisabetta Dejana, Bin Zhou and Ralf H. Adams*. Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells. (2016)?Nature Communications.?7:12422 doi: 10.1038/ncomms12422.?
(11) Qi Chen#, Luan Jiang#, Chun Li, Dan Hu, Ji-wen Bu, David Cai, Jiu-lin Du*.Haemodynamics- Driven Developmental Pruning of Brain Vasculature in Zebrafish. (2012)?PLoS Biology?10(8): e1001374.?#Equal contribution
被Nature選為亮點(diǎn)論文：Highlight in Neurodevelopment: Low flow blood vessel pruning. Nature (2012) 488(7413): 560.?
PLoS Biology專門評論文章 (2012) Pruning Brain Vasculature for Efficiency. PLoS Biol 10(8): e1001375
